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New and experimental HIV treatments
Dolutegravir matches raltegravir for people starting treatment

The novel integrase inhibitor dolutegravir worked as well as raltegravir (Isentress) at 48 weeks for treatment-naive people in the Phase III SPRING-2 study, according to a late-breaker

Published
27 July 2012
By
Liz Highleyman
PrEP
High levels of adherence reached in two PrEP studies, but resistance cases show need for rigorous testing before prescribing

Two studies of pre-exposure prophylaxis (PrEP) in heterosexuals in Africa, both of which reported significant efficacy in preventing HIV infection last year, published their final results in the

Published
20 July 2012
By
Gus Cairns
Resistance
Researchers find that pre-existing mutations can lead to drug resistance in HIV virus

In a critical step that may lead to more effective HIV treatments, Harvard scientists have found that, in a small number of HIV patients, pre-existing mutations in the virus can cause it to develop resistance to the drugs used to slow the progression of the disease.

Published
08 June 2012
From
Medical Xpress
Adherence
HIV treatment breaks lead to drug resistance in the female genital tract

Antiretroviral treatment interruptions of 48 hours or more are associated with the emergence of resistant strains of HIV in the female genital tract, investigators report in the

Published
24 May 2012
By
Michael Carter
Resistance
UGANDA: Rising ARV resistance threatens HIV fight

The prevalence of drug-resistant HIV strains in Uganda has risen from 8.6 percent to 12 percent in the last five years, one of the highest rates in Sub-Saharan Africa, according to a recent study.

Published
22 May 2012
From
IRIN Plus News
Resistance
Transmitted HIV Drug Resistance on the Rise in U.S.

New surveillance data from the U.S. Centers for Disease Control and Prevention (CDC) suggest that about two in 10 individuals diagnosed with HIV in recent years were infected with HIV strains harboing mutations conferring at least partial resistance to one ore more available antiretroviral (ARV). The report was presented Wednesday, March 7, at the 19th Conference on Retroviruses and Opportunistic Infections in Seattle.

Published
21 March 2012
From
AIDSMeds
How HIV causes disease
Superinfection: second HIV infections happen as often as first ones

Two studies of people with HIV in Rakai, Uganda and Mombasa, Kenya presented at the 19th Conference on Retroviruses and Opportunistic Infections show that the rate at

Published
10 March 2012
By
Gus Cairns
Outcomes and prognosis
Second-line treatment failure most often due to poor adherence in low and middle-income countries

Poor adherence rather than drug resistance appears more likely to be the cause of virological failure among patients on second-line ART in resource-poor settings, according to a systematic

Published
24 February 2012
By
Carole Leach-Lemens
PrEP
UCLA researchers suggest unconventional approach to control HIV epidemics

Because PrEP is based on the same drugs used to treat HIV-infected individuals, the big public health scare is that the dual use of these drugs will lead to skyrocketing levels of drug resistance. In fact, say UCLA researchers in a new study, that is not the case and indeed, the exact opposite is likely to happen.

Published
07 December 2011
From
Eurekalert Medicine & Health
Resistance
Microsoft Research: Spammers Act Just Like HIV Virus In Avoiding Filters

Security researchers often use language and metaphors from the natural world to describe problems in the virtual world. (Thus, our use of the terms "virus," and "worm.") Now it turns out that the links may not be so arbitrary, after Microsoft researchers discovered that tools they developed to detect spammers' efforts to avoid anti-spam filters were also great at spotting mutations in the HIV virus.

Published
03 December 2011
From
ThreatPost.com
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